Metabolic health crises have never been a more pressing issue as they are today. Estimates, in fact, suggest that 1.5 billion adults worldwide suffer from Metabolic Syndrome, a range of disorders including diabetes and cardiovascular disease, among other chronic conditions.
With obesity rates and sedentary lifestyles on the rise, this figure will likely increase in the coming years, according to a September 2025 study.
At a moment when patients are experiencing metabolic stress, inflammation, and insulin resistance, is the traditional framework efficiently addressing the current nutrition landscape?
Many of the nutritional recommendations are becoming repetitive; paradigms of “one-size-fits-all” solutions, calorie counting, and macronutrient management appear to be failing to address the invisible, individual physiological responses that underlie disease risk.
Alternate approaches are appearing on the market, however. Nutrition is no longer just about what we eat, but also about our bodies’ response to it.
Such is the core promise behind ResetRX, which has designed a holistic model that measures key biomarkers associated with longevity and turns them into practical guidance for daily well-being.
To optimize health at an individual and personalized level, the company translates the measured data into personalized wellness plans with recommendations for concrete actions. Along this path, the platform offers expert coaching support to track daily progress.
CEO Bryan Janeczko has been a key player in that shift. His vision reflects a promising future in nutritional intelligence: biological data, real-time insight, and personalized feedback will redefine what it means to eat well in a world where generic rules are no longer the answer.
“We optimize your health by measuring clinically validated biomarkers predictive of longevity, translating them into concrete, personalized wellness plans across key lifestyle pillars with expert and coaching support to track your progress each step of the way,” he told StartupBeat.
From early algorithms to real-time biomarkers
Janeczko was among the early adopters of precision nutrition, digital tools to tailor eating habits around personal differences. These early algorithms attempted to interpret patterns in behavior and biology long before wearable sensors or continuous metabolic monitoring entered mainstream use.
“As a pioneer in precision nutrition, I recognized early on how important technology could be in understanding what it means to eat well,” he said.
“Fifteen years ago, we developed algorithms, before today’s genAI tools, to help individuals optimize healthy eating based on their biology and behavior.”
Back then, available data was limited, but the shift was already beginning: the future of nutrition would no longer be founded on general rules, but on how each body responds uniquely.
Today, the field looks dramatically different. Countless wearables and apps can track sleep and stress patterns; at-home tests can measure glucose variability, inflammation, and hormone balance; AI models can interpret complex inputs in real time.
Biomarkers have posed the real revolution, however. As physiological indicators- including glucose levels, inflammatory markers, lipid profiles, and hormones- they provide real-time insight into how an individual’s body processes and reacts to nutrition and lifestyle inputs.
“Today, we have so much more data in our hands, and combined with biomarker testing, we are connecting the dots between how we eat and how our bodies actually respond in real time,” Janeczko explained.
The integration of biomarker testing into their algorithms has made invisible reactions measurable. What someone eats on a day of poor sleep or during periods of stress, for example, may affect their biology differently than on a well-rested day.
In this case, ResetRX uses biomarker insights to help users personalize aspects like nutrition, so “it works for their biology and not against it.”
Turning data into decisions: the next leap in personalized guidance
Even as biomarker data becomes more accessible, real-time interpretation remains one of the most persistent challenges. We move through our days surrounded by overwhelming metrics- sleep durations, glucose fluctuations, stress indicators, step counts. How could we make sense of them?
The CEO sees this as the next frontier of nutrition and healthspan innovation:
“We are making rapid progress training Eva, our human-centered, AI-driven health coach,” he said. Eva’s purpose is to turn biomarker and lifestyle data into personalized, actionable suggestions that guide wellbeing decisions.
Designed to bridge the gap between complex physiology and everyday decision-making, the AI coach aims to blend empathy with evidence around five core pillars: voice and tone, governance, user context, scientific foundation, and behavioral framework.
For example, while a user writes “I didn’t sleep well and have a 7 am meeting. Should I still work out?” Eva reviews their recent data and prior habits and may respond with:
“Since your sleep was under six hours, today’s best move is a 20-minute walk and a protein-rich breakfast. You will support recovery without spiking cortisol. Think long game, not burnout.”
The small interaction is illustrative of a larger vision: personalized coaching that adapts to an individual’s biology, environment, and behavior. For ResetRX, Eva represents the next generation of healthspan guidance.
Democratizing nutrition insights
Transparency in food and health data has often been a privilege tied to access, cost, or expertise. In turn, Janeczko points to democratization as core to the company’s purpose:
“Transparency has always been an issue. The good news is that it is breaking down, and technology is the primary accelerant for that.”
What once required elite coaching or concierge medicine is now available through at-home testing, digital tools, and 24/7 access to information. In this, nutrition is welcoming the same access leveling as fintech brought to investing.
“[We’re] taking the kind of precision data once reserved for elite athletes or the wealthy and making it accessible to anyone who wants to feel better and age well,” the executive stressed.
But, this shift also raises questions about accuracy, interpretation, and equitable access. As technology enables the democratization and transparency of information, the need for science-based frameworks increases.
These should help users understand and benefit from their own data. Companies like ResetRX are vital in this landscape, as they develop tools grounded in research to support such a transition.
Toward a new framework: prevention and eating what works for your biology
When asked what the next revolution in nutrition will look like, Janeczko pointed to three main aspects: technological, ethical and social.
From his perspective, technology will sharpen precision; ethics will demand transparency and sustainability; and society will shift toward prevention rather than repair.
“Someone is eating copious amounts of bacon or saturated fats, then has a heart attack… the response? Eat less bacon, which occurs after the fact,” he said, illustrating an outdated reactive approach to health.
However, ResetRX is betting on the growing awareness of preventative and personalized measures: what Janeczko deems “nutritional intelligence”.
By shifting from the standardized diet culture, he wants to lead the path to where “the right foods for you depend on your biology, your environment, and your lifestyle.”
And, in his view, this transformation will also reshape how society defines healthy eating:
“The future isn’t just about eating better food. It is about eating what’s better for you.”
That future is not far off. ResetRX’s app, currently in private beta, is set for public release in January, offering users a first look at how biomarker-driven insights can shape long-term wellness.
